FRONTLINE Plus Flea and Tick Treatment for Large Dogs Up to 45 to 88 lbs. 3 Treatments
65 in stock
FRONTLINE Plus Flea and Tick Treatment for Large Dogs (45–88 lbs) – 3 Treatments
Keep your large dog protected with FRONTLINE Plus, the #1 name in flea and tick protection, trusted by pet owners and veterinarians for nearly 20 years. This pack delivers 3 monthly treatments — a full 3-month supply — specially formulated for dogs weighing 45–88 lbs.
FRONTLINE Plus combines two powerful active ingredients — fipronil and (S)-methoprene — to break the flea life cycle at every stage. Fipronil quickly kills adult fleas and ticks by attacking their nervous system, while (S)-methoprene works to prevent flea eggs from hatching and stops larval development, guarding against future infestations. This dual-action approach doesn't just treat existing pests — it actively stops new ones from taking hold.
Applied to a single spot between your dog's shoulder blades, the treatment is absorbed into the sebaceous (oil) glands beneath the skin, which act as a natural reservoir — continuously replenishing protection over your dog's entire body, even after swimming or bathing. FRONTLINE Plus effectively controls major tick species, including brown dog ticks, American dog ticks, lone star ticks, and deer ticks (which can transmit Lyme disease), as well as chewing lice, and helps manage sarcoptic mange with regular use.
✨ Key Highlights:
- 3 treatments — a full 3-month supply
- For dogs and puppies 8 weeks or older, weighing 45–88 lbs
- Active ingredients: Fipronil 9.8% and (S)-methoprene 8.8%
- Kills fleas, flea eggs, flea larvae, chewing lice, and ticks
- Waterproof and long-lasting — one dose per month
- Trusted flea & tick brand for over 20 years
- Fast-acting, easy single-spot application
- No prescription required

